How it works

Ciclosporin inhibits the production and release of proteins called lymphokines from T cells, which are a type of white blood cell. Lymphokines attract additional immune cells to mount an immune response, such as generating antibodies. In myasthenia, antibodies block muscle cells from correctly communicating with nerve cells, resulting in muscle weakness. By reducing the production of antibodies, Ciclosporin can mitigate some of the symptoms of myasthenia.

How it is delivered

Ciclosporin can be delivered orally as a tablet or liquid but can also be given by injection. Your dose is weight-based.

When you have it

Ciclosporin is generally taken twice daily, ideally with 12 hours separating the two doses. You should ideally take Ciclosporin on an empty stomach, or at least 1 hour before, or 2 hours after a meal as food can affect its absorption. The benefits of this medication are usually seen within days of starting medication.

Side effects

All new medicines can cause unwanted side effects. When starting Ciclosporin, you may experience these side effects initially, but they should improve as your body adjusts over a few weeks. Some people may not experience any side effects. You will have routine blood tests to check for any adverse effects. Some side effects to be aware of are:

• Nausea and tiredness
• Increased hair growth
• Slightly enlarged or sore gums

If these symptoms persist, please consult your doctor. Some side effects, like high blood pressure, can be reverse by reducing your dose of Ciclosporin. Please check the patient information sheet for an extended list of possible side effects. If you have any questions or concerns, always check in with your doctor. You may also find it reassuring to contact the team at myaware.

Known UK suppliers

Colorama Pharmaceuticals Ltd, Ennogen Healthcare Ltd, Phoenix Healthcare Distribution Ltd, Sigma Pharmaceuticals Plc.

FAQ (what else do I need to know?)

Be vigilant to any allergic reaction that can arise in response to Ciclosporin. If any symptoms of anaphylaxis occur when taking Ciclosporin (very fast or irregular breathing, gasping for breath, wheezing, or fainting) stop your treatment and contact your doctor immediately.

Grapefruit can increase Ciclosporin levels in your blood, and should be avoided in the hour before you take the capsules.

Alcohol can be consumed within moderation when undergoing treatment with Ciclosporin.

You should avoid becoming pregnant whilst taking Ciclosporin and should not breastfeed if still receiving treatment.

Report any side effect you have to the Medicines Health and Regulatory Authority (MHRA) as part of their Yellow Card Scheme.

Click here to report a side effect to the MHRA.

Treatments